In 2021, Demetriou was a series regular on the second series of This Time with Alan Partridge, portraying a flirtatious makeup artist named Tiff. The eight-part series sees 10 pairs of contestants in a knockout competition featuring huge flower installations with the winner going on to design an installation to be displayed in London's Royal Botanic Gardens, Kew. Starting, Demetriou and Vic Reeves co-hosted Netflix's unscripted reality competition show The Big Flower Fight. The second season of ten episodes debuted in April 2020. The show co-stars Kayvan Novak, Matt Berry, Harvey Guillén and Mark Proksch. The mockumentary follows three vampires (Laszlo, Nadja, and Nandor) living in a house in Staten Island and trying to cope with modern-day New York City, along with an energy vampire (Colin) and Nandor's human familiar (Guillermo). The series was created by Jemaine Clement and Taika Waititi, based upon their 2014 film of the same name. Since March 2019, Demetriou has starred as Nadja, a Greek Romani vampire, in the critically acclaimed FX horror comedy series What We Do in the Shadows. In March 2020, it was reported that BBC commissioned a six-episode series, but it was delayed due to the COVID-19 pandemic. In 2019, Demetriou also starred in and wrote the highly acclaimed BBC Three comedy sketch show Ellie & Natasia, a show inspired by social anxiety and being a woman in today's society, with Ellie White. At the 2020 BAFTA awards Stath Lets Flats won three awards: Best Male Actor in a comedy, Best Writer of a Comedy, and Best Scripted Comedy. On, a special "lockdown" mini-episode was released online due to the COVID-19 pandemic. In 2018 she played sister to her real life brother Jamie Demetriou's Stath in Channel 4 sitcom, Stath Lets Flats, about a family-run estate agents, which was written and created by her brother. In 2015, she was in the comedy sketch show pilot of People Time on BBC Three with Ellie White, alongside her brother Jamie Demetriou, with Claudia O’Doherty, Liam Williams, Alistair Roberts and Daran Johnson. She was a longtime member of sketch comedy troupe Oyster Eyes and has written for Anna & Katy and The Midnight Beast.
Career ĭemetriou's debut show, You'll Never Have All of Me, won the Skinny Debutant Award at the 2014 Edinburgh Festival Fringe.
Prior to becoming a professional comedian, Demetriou worked as a makeup artist, notably working on music videos for Boy Better Know. She studied acting at University of Leeds. Her younger brother, Jamie Demetriou, is a comedian and actor with whom she often collaborates. Natasia Charlotte Demetriou was born in London, the daughter of an English mother and a Greek-Cypriot father.